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Presented for research literature review only Schumacher CP et al
The future prospects of targeting the PPP in disease treatment are promising
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GLP-1 and GIP receptors are found in the brain, alongside fat cells, pancreatic beta cells and other tissues involved in metabolism
Therefore, the results of ongoing CVD outcome trials with the use of GLP-1 RAs should be awaited to elucidate the translation of benefits previously seen in CVD risk marker studies into large clinical trials with primary cardiovascular outcomes
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