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Methotrexate also forms polyglutamates that inhibit other enzymes such as thymidylate synthase and aminoimidazole carboxamide ribonucleotide transformylase (AICART), resulting in the accumulation of adenosine, a potent anti-inflammatory mediator

Vegetables (pick 3-4): Roast a sheet pan of broccoli, sweet potatoes, and bell peppers

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These factors generate free radicals that damage skin cells and speed up aging

Heavy lifting when your energy is already depleted leads to poor performance and increased injury risk