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Additionally, if tirzepatide enables corticosteroid dose reduction, the bone-protective effects of lower steroid exposure could outweigh any bone density loss from weight reduction

Doctors have been prescribing the drugs off-label as a treatment for obesity

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Retatrutide improved fasting lipid profiles including triglycerides, very low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol in clinical trials in people with T2D or obesity, while low-density lipoprotein cholesterol was reduced in people with obesity 12,13,28

This article looks at how Orexin A peptide may help with daytime fatigue