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In vivo experiments further demonstrated that Irisin-loaded bone marrow mesenchymal stem cell-derived exosomes significantly inhibited activation of the YAP/EGR1/ACSL4 signaling pathway in the brains of middle cerebral artery occlusion (MCAO) mice, suppressed ferroptosis and lipid peroxidation, thereby mitigating ischemic brain injury ( In vitro experiments further confirmed that FGF21 protected HT22 cells from OGD/R-induced oxidative stress and ferroptosis, thereby attenuating neuronal injury (Zhao et al., 2025c)

Glutathione is often hailed as the master defender because of its key role in cell protection

Authors also thank the Slovak Grant Agencies VEGA Project 1/0542/24 and Project APVV 190087

This documentation helps identify patterns if research results seem inconsistent

Whatever form of turmeric you choose, consider combining your supplement with black pepper