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If your levels are already normal, a shot mainly keeps you topped off rather than creating a big surge
Medically Reviewed on 6/10/2026 Harvard T
A B12 deficiency can happen due to age, low absorption, low IF levels, or diet
New or unexpected symptoms : Whilst rare, allergic reactions to hydroxocobalamin can occur
Keep in mind this is one marker, and lowering it has not by itself been proven to prevent heart attacks or strokes
Some patients notice improved energy or mental clarity within 2448 hours, whilst others experience no immediate change, particularly if deficiency is severe
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