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Appetite changes often occur early in treatment
Semaglutide only works in conjunction with a healthy diet and plenty of physical activity
In turn, this would likely result in weight gain and the return of co-morbidities
Bone density loss
an early phase 1b study reported that co-administration was feasible and that each components pharmacokinetics were not meaningfully altered by the other, which motivated the phase 3 program [3]
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