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These formulations provide targeted pain relief with minimal systemic absorption, significantly reducing the risk of gastrointestinal and renal side effects compared to oral NSAIDs

Patients should avoid activities requiring alertness, such as driving or operating machinery, if experiencing significant dizziness

The medication is initiated at 2.5 mg once weekly for 4 weeks, serving as a tolerability dose rather than a therapeutic dose

Leger, PhD, CDCES, CCRC, and Jean Young Park, MD

Stimulus checks

The STEP 1 trial evaluated 1,961 adults taking Wegovy who were overweight or who had obesity but did not have Type 2 diabetes