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Anti-angiogenic properties of several organosulfur compounds, including alliin, DATS, and ajoene, have been observed in in vitro or ex vivo experiments (70)
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Using a sensitive analytical technique called mass spectrometry, they tracked the peptide as it was broken down by enzymes naturally present in the blood, and identified all the fragments that were produced
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Additionally, ketamine activates the NLRP3 inflammasome, inducing caspase-1 activation and neuronal pyroptosis, further contributing to neuroinflammation in regions, such as the hippocampus and prefrontal cortex (Zhang et al., 2021)
The next step should be reassessment, not only dose escalation
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