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The extraction solvent consisted of 80% methanol and 20% aqueous solution (pH 7.00) containing 10 mM ammonium formate (Sigma-Aldrich, 70221-25G-F) and 25 mM NEM (Thermo Scientific, 040526.06)

NAD-sensitive hydrogel for the release of macromolecules [PMID: 15329937] Laboratory literature summary: NAD-sensitive hydrogel for the release of macromolecules

This raises theoretical concerns about affecting levothyroxine absorption, though the evidence is less definitive than with oral semaglutide

doi:10.5664/jcsm.6034 Cheng AC, Wu GJ, Chung CH, et al