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23 Adverse reactions and tolerability: The DPP-4 inhibitor class of medications is generally very well tolerated, although post-marketing reports have described serious adverse events (see Warnings and precautions section)

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The Lancet Healthy Longevity, Volume 5, Issue 9, 100632 3 Targher, G., Mantovani, A

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Protection against reactive oxygen species by selenoproteins

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And NAD itself doesnt efficiently enter cells

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