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The data comes from the Phase 2 SURMOUNT trial involving 338 participants across all dose groups, with the most comprehensive data available for the 12mg maintenance dose

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According to the medicines' SmPCs, no dose adjustment is generally required for patients with mild to moderate hepatic impairment

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Under normal circumstances, your body can produce enough glutamine on its own, but during times of high physical stress, your needs may exceed your body's ability to keep up

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is highly expressed in mouse tissues with metabolic function