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The most common polymorphisms of GSTM1-1 and GSTT1-1 gene loci consist in the complete deletion of the genes
Requires ongoing use for maintenance Some user reports indicate that benefits diminish after stopping the product
These potential benefits, however, come with high costs that raise concerns about the impacts on public and private payers
The boxed warning also mentions the risk of pancreatitis and that the medication is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) and patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
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