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Therapeutic potential of puerarin against methioninecholinedeficient dietinduced nonalcoholic steatohepatitis determined by combination of 1H NMR spectroscopybased metabonomics and 16S rRNA gene sequencing
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Ischemiareperfusion injury exhibits a biphasic ROS burst: xanthine oxidase activation during hypoxia synergizes with mitochondrial electron leakage during reperfusion, causing calcium overload and contractile dysfunction [325]
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Non-fibrogenic type IV collagen is replaced by fibrogenic type I and II collagen (Figure 1B)
