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How Long Does Cold Sensitivity Last on GLP-1 Treatment Most patients report that cold sensitivity diminishes significantly after 812 weeks of consistent treatment, though the timeline varies based on individual metabolism and genetic factors
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Dose decisions should be based on patterns over multiple weeks, not a single weigh-in
This is one of the reasons published Tirzepatide research is typically discussed not only in terms of efficacy, but also in terms of tolerability during escalation , GI event burden and the balance between metabolic benefit and dropout risk
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