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We advise that you do not use Mounjaro or Wegovy alongside Orlistat or Xenical, as their effects on weight loss and digestion can overlap
The effect of currently approved GLP-1 monotherapies for T2D on weight loss are presented in Table 2
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doi: 10.1371/journal.pone.0073358 77
If your weight loss is too rapid or profound, you may sacrifice muscle mass (sarcopenia), which can lead to a marked decrease in appetite and difficulty consuming enough protein
GLP-1 inhibits glucagon release (which slows down the release of sugar into the blood so that you burn more fat), slows down gastric emptying (makes you feel full), and lowers the desire for food intake (because you feel full)
