Potential for Hypoglycemia: Because tirzepatide impacts insulin sensitivity, people with diabetes need to be extra cautious about low blood sugar episodes
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Most side effects are temporary and may improve as the body adapts
October 2025 : The Wegovy warning label was updated to include Severe Gastrointestinal Adverse Reactions in the WARNINGS AND PRECAUTIONS section
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Likewise, side effects from this drug are more specific to the muscles, including spasms, but its ability to increase lean mass at the expense of fat suggests that it may find use in combination with other drugs to ensure body weight loss is preferentially targeted towards fat, while ensuring muscle is spared