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Similar anti-fibrotic effects of liraglutide have been reported in a streptozotocin (STZ)-induced diabetic model, where liraglutide reduced -SMA, collagen I and fibronectin expression and altered the renal proteome consistent with decreased oxidative stress and attenuated ECM deposition [57]

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For patients who prefer to pay out-of-pocket first and request reimbursement, PlexusDx provides itemized invoices clearly labeled as medical treatment expenses

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Established options include single GLP-1 receptor agonists like semaglutide (Wegovy, Ozempic) and dual GIP/GLP-1 receptor agonists like tirzepatide (Zepbound, Mounjaro)

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The blood-brain barrier obstacle The BBB is a selective semipermeable interface between neuronal tissue and blood vessels that form the neurovascular unit, with the main role of helping normal brain homeostasis, regulating influx and efflux transport, and ensure protection, mediating the communication between CNS and peripheral one (Rhea and Banks, 2019)

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Scheduling follow-up visits ensures side effects are managed early and treatment remains effective

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