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Tesamorelin's modified structure gives it the longest practical half-life of the three GH-axis peptides, while sermorelin's is the shortest
Common Reflux Triggers on GLP-1s Very spicy foods chilli-heavy dishes, hot sauce, curry with high capsaicin content Tomato-based sauces pasta sauce, pizza sauce, tomato soup (particularly on an empty stomach) Citrus fruits and juices oranges, grapefruit, orange juice Chocolate relaxes the lower oesophageal sphincter Peppermint including peppermint tea (also relaxes the LES) Carbonated beverages even sugar-free ones increase pressure and reflux Coffee, particularly on an empty stomach combines acid stimulation with LES relaxation Onions and garlic in large quantities some patients report significant reactions What to eat instead: Mild-flavour proteins, cooked vegetables (steamed, roasted), plain yoghurt, oats, bananas, ginger tea (actually helps reduce nausea)
This causes ghrelin to rise and leptin to fall
Oral semaglutide for type 2 diabetes: a systematic review and meta-analysis
Even more exciting, when we discontinued the GLP-1 drug but continued anti-CRH, the mice maintained their weight loss, largely because they naturally ate less
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