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Supporting your body's natural "cleanup" processes from the inside out is often more effective than relying solely on topical treatments
A nine-week, randomized, controlled trial of healthy, resistance-trained men found that HMB supplementation had a clear bolstering effect on fat-free mass and substantially strengthened lower-body muscles compared to the placebo group[10]
With respect to the wider GLP-1 drug class, the UK SmPCs for semaglutide (available on the electronic Medicines Compendium, emc) and tirzepatide (Mounjaro SmPC, emc) document GI adverse effects including nausea, vomiting, diarrhoea, constipation, and dyspepsia as well-characterised class effects
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