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For instance, the development of autoimmune diseases is stimulated by iodine (excess or deficiency), smoking, stress, and chemical contaminants (like polyaromatic hydrocarbons), medicine (like amiodarone and interferon-alpha (IFN), and bacterial and viral infections (like hepatitis C virus and Yersinia enterocolitica)

10.1016/j.yebeh.2015.05.040 219

The clinical results are unprecedented, with patients achieving 15 to 21% total body weight reduction in landmark trials

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Indian Journal of Endocrinology and Metabolism, 20 (5), 720724

Presented for research literature review only Nahata MC et al