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The special formulation that allows for rapid dissolution may not be uniformly distributed throughout the tablet, meaning that splitting could result in uneven doses of the active ingredients
In addition to a 2030% reduction in albuminuria compared to placebo, GLP-1 receptor agonists (GLP-1RAs) decelerate the decline of estimated glomerular filtration rate (eGFR) by 12 mL/min/1.73m2 per year relative to usual therapy (Granata et al
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Understanding what this combination actually does, how the two molecules interact, and whether the theoretical benefits translate into real-world outcomes requires looking past marketing claims and into the biochemistry
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