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Tirzepatide may lead to greater weight loss for some patients because it targets both GLP-1 and GIP pathways
GLP-1s may decrease the frequency of flareups in HS by modifying immune pathways and lowering CRP
This cardiovascular outcomes trial of semaglutide versus placebo in patients with type 2 diabetes at high cardiovascular risk revealed an unexpected finding: patients receiving semaglutide experienced a statistically significant increase in diabetic retinopathy complications (hazard ratio 1.76, 95% CI 1.112.78, p=0.02)
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In addition to these favorable features, semaglutide, similarly to other GLP-1 RAs, offers beneficial effects on cardio-vascular (CV), renal, and liver protection, making this molecule an advantageous choice in the therapeutic management of diabesity (coexistence of both diabetes and obesity) and its co-morbidity
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