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In particular, lower levels of adiponectin and increased expression of TNF- and its soluble receptor have been recently related to the development of NASH ( Most patients with NAFLD are asymptomatic, and the diagnosis is mainly made incidentally on the basis of liver biochemistry or abdominal ultrasound abnormalities

Marcel Dekker, New York, pp

P.GillenJ

2015 Mar;7(3):259-64

Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach