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Diarrhoea and constipation are also common side effects, caused by how the drugs change how the bowel moves and how secretions are released into the bowel

Brand-name tirzepatide comes in single-dose pens or pre-filled syringes with minimal air exposure

It slows gastric emptying, which helps control blood sugar and prolongs satiety

Weight Loss Comparison: Retatrutide vs Tirzepatide vs Semaglutide How does retatrutide compare to the current standard of care

DPP-4 inhibitors (Januvia): These medications work by increasing insulin release and decreasing the amount of glucose produced by the liver

Varady, K.A., Hellerstein, M.K