When to See a Doctor While mild vitamin B12 deficiency may go unnoticed in the early stages, certain symptoms should not be ignored, especially if they begin to interfere with daily life or worsen over time
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Megadoses of up to 2,000 mcg are considered safe in treating a B12 deficiency, but its best to avoid excessive amounts of any vitamins, especially when not needed
It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not how full you feel. That mechanistic distinction is the single most important thing to understand before looking at any dose number
A serum B12 level test and ideally a methylmalonic acid test should be performed before starting B12 injections
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