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55 The authors reported that NAMPT-null (NAMPT / ) mice showed embryonic lethality at early stages, and the adult mice die within 510 days after NAMPT depletion
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In-vivo tests using alloxan-induced diabetic rats demonstrated that compounds 13, 14, and 15 (Figure 4) displayed significant anti-diabetic activity, with lower blood glucose levels in diabetic rats compared to control rats
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