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Semaglutide medications, like Ozempic, Rybelsus and Wegovy, work by mimicking a hormone known as glucagon-like peptide-1 (GLP-1)

Early or experimental findings: Researchers have investigated possible effects involving the brain and inflammatory pathways

Brain-gut Axis and pentadecapeptide BPC 157: Theoretical and practical implications

heat for muscle tension and chronic pain Exercise and movement : Regular physical activity is recommended by NICE as a core treatment for many pain conditions and is also beneficial for weight management alongside Wegovy Psychological approaches : Cognitive behavioural therapy (CBT) and mindfulness-based stress reduction for chronic pain, with strong evidence supporting their effectiveness Topical preparations: Topical NSAIDs (such as ibuprofen gel) and capsaicin cream provide localised pain relief with minimal systemic absorption, making them particularly suitable for patients concerned about drug interactions or those with gastrointestinal sensitivity

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