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Cho SG, Lee YH, Park HS, Ryoo K, Kang KW, Park J, Eom SJ, Kim MJ, Chang TS, Choi SY, Shim J, Kim Y, Dong MS, Lee MJ, Kim SG, Ichijo H and Choi EJ
Materials and Methods Chemicals Ferric chloride, di-sodium hydrogen phosphate (Na 2 HPO 4 ), hydrogen peroxide (H 2 O 2 ), di-potassium hydrogen phosphate (K 2 HPO 4 ), potassium di-hydrogen phosphate (KH 2 PO 4 ), and carboxymethylcellulose (CMC) were procured from MERC, India Ltd., Mumbai, whereas hesperidin, 1-Chloro-2,4-Dinitrobenzene (CDNB), phenazine methosulphate, nitroblue-tetrazolium, sodium pyruvate, cumene hydroperoxide, thiobarbituric acid, 5-5-dithiobis[2- nitrobenzoic acid, 5-thionitrobenzoic acid, mM tert-butylhydroperoxide and nicotinamide adenine dinucleotide (NADH) were supplied by the Sigma Aldrich Chemical Company, Kolkata, India Animal care and handling The animal care and handling were performed in accordance with the guidelines issued by the World Health Organization, Geneva, Switzerland and the INSA (Indian National Science Academy, New Delhi, India)
10.1016/0140-6736(91)90350-x Lancet
ROS production and associated inflammation are closely related to aging and numerous chronic diseases as diabetes, cardiovascular and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease
Anxiety disorder, major depression, bipolar depression, and schizophrenia are also linked to the microbiome-gut-brain axis
Garlic, onions, and cruciferous vegetables like broccoli, kale, and Brussels sprouts are excellent choices
