The direct effect of exercise on GLP-1 in people is smaller and less consistent than its broader metabolic benefits, so the honest framing is that movement supports the whole system rather than acting as a GLP-1 amplifier
For the full legal and availability picture, see Is Retatrutide Available Yet
Blonde L, Meneghini L, Peng XV, et al
Improvements in body composition: Some studies show modest increases in lean body mass and reductions in fat mass, particularly in older adults with documented GH insufficiency
These are usually mild to moderate, occur mainly during dose titration, and typically diminish as the body adjusts to the medication
Proper patient selection, baseline blood work, and ongoing clinical monitoring are essential to ensure the therapy is safe, effective, and correctly tailored to the patients specific metabolic needs