Nrf2, a member of the capncollar family of basic regionleucine zipper transcription factors involved in transcription of antioxidant genes in response to xenobiotic stress, is also a critical regulator of cellular oxidative stress in sepsis (Kolls, 2006) and a regulator of exacerbated proinflammatory cytokine release (cytokine storm) and loss of T lymphocytes (leukopenia) that characterize the most aggressive presentation of SARS-CoV-2-mediated COVID-19 infection (Kobayashi et al., 2016
Both are regenerative actives with strong mechanism evidence
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Daily application of the serum between treatments enhances cumulative improvements
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PubMed Bock-Marquette, I., Saxena, A., White, M.D., Dimaio, J.M., & Srivastava, D