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Eight major RCTs of GLP-1RAs have investigated the cardiovascular outcomes, including the ELIXA trial of lixisenatide (250), the EXSCEL trial of exenatide ER (251), the LEARDER trial of liraglutide (252), the SUSTAIN-6 trial of subcutaneous semaglutide (253), the HARMONY trial of albiglutide (228), the REWIND trial of dulaglutide (254), the PIONEER trial of oral semaglutide (255), and the SELECT trial of subcutaneous semaglutide (199)
We have way more real-world data for Ozempic than we do for tirzepatide
Horn, an obesity medicine expert at UTHealth Houston in Texas, tells Fortune that it is always reassuring to see results from a controlled environment like a clinical trial reproduced in the real world, and added that the HbA1c and weight changes mirror what she sees in patients
The 2.5 mg dose is meant for treatment initiation only
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Our study showed no differences for VitD and OCN at baseline between those with osteoporosis and without osteoporosis at follow-up
