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Much of the public conversation around drugs such as Wegovy and Ozempic focuses on weight loss results

The shortage began in 2022 and has been extended several times due to changes in demand

Atherosclerotic CVD manifest as heart attacks and strokes, is responsible for up to 85 per cent of cardiovascular deaths [1]

3 Side effects typically improve over time with both medications

To reconcile the findings that both GIPR antagonists and GIPRAs reduce body weight, it is possible that physiological GIPR activity plays a permissive role in adipose tissue synthesis, while pharmacologically enhanced GIPR activity may reduce body weight through a different mechanism in the brain

Vargas-Soria, M., Carranza-Naval, M