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MTX is used in dose-dependent manner, which demonstrates that the treatment dose varies depending on the disease to be treated
If P53 activity is inhibited due to lack of DINO lnc RNA, it is the DINO promoter which must be targeted
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It upregulates 1,584 genes associated with tissue repair, stem cell biology, and antioxidant defense, while downregulating 2,550 genes linked to inflammation, fibrosis, insulin resistance, and cancer metastasis
Presented for research literature review only Hargus SJ et al
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