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Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement
Investigation 79 (2), 616619
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Medication program persistence and engagement: January 2026 analysis of 30,239 Noom GLP-1 Rx Program members who started a GLP-1 Rx plan between December 2024 and February 2025, evaluating program persistence by engagement quartile
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