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The mechanism involves both peptides effects on remodeling: BPC-157 promotes organized collagen synthesis, while TB500 limits excess fibroblast proliferation and supports proper architecture

doi: 10.1186/1297-9716-43-75 79 FlahouBHaesebrouckFChiersKVan DeunKDe SmetLDevreeseBet al

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It is noteworthy that long-term HFD consumption may differentially regulate NF-B activity in hepatocytes (inhibition) and Kupffer cells (activation by lipopolysaccharide)