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This was attributed to the effect of iron chelation on dopamine synthesis due to the inhibition of the activity of the iron-dependent tyrosine hydroxylase
Some of the primary genes impacted are COL1A1 (matrix), VEGFA (angiogenesis), IL6 (inflammation), and SOD2 (oxidative defense)
Feb 2022;61(1):413-428
, 26 , 315-322, doi: Tak, H., Kang, H., Ji, E., Hong, Y., Kim, W., and Lee, E
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Environmental toxins and UV exposure create oxidative stress
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