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Moreover, it has been proven that gorging induced by obvious hunger after zero-calorie fasting has a harmful effect on health, especially with respect to weight gain [23]

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Additionally, the FTO rs9939609 variant influences baseline metabolic rate and fat-storage tendency, affecting how much your metabolism shifts on treatment

10.3389/frph.2022.1030949 46 YangL.ChenY.LiuY.XingY.MiaoC.ZhaoY.et al (2021)

The article suggests natural alternatives may be appropriate first-line options for people with mild metabolic dysregulation, no severe comorbidities, and realistic expectations about outcomes

For long-term use , GLP-1 Elevate is a sustainable, non-habit-forming option