And from 2019 to 2024, the percentage of adults prescribed a GLP-1 to treat obesity rose from 0.30% in 2019 to 2.05% in 2024, an increase of 586.7%
Components included cardiovascular-related death, kidney-related death, persistent 50% estimated glomerular filtration rate (eGFR) reduction, persistent eGFR 15 mL/min/1.73m 2 , and chronic kidney replacement therapy
It mimics the effects of a naturally occurring hormone in our bodies known as glucagon-like peptide-1 (GLP-1)
Bateman RJ, Benzinger TL, Berry S, Clifford DB, Duggan C, Fagan AM, et al
Persistent or severe diarrhea warrants medical evaluation to rule out other causes and prevent dehydration
Some tolerate higher doses well and benefit from faster escalation