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Hemachand T, Shaha C

Starting Price 13.99 Availability In stock Variants 2 options *All compounds are sold strictly for laboratory research use only

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Then, the cells were resuspended in 0.2 M phosphate buffer (pH7.0) containing different concentrations of l-cysteine or GSH and 0.5 % (v/v) toluene, and the reaction mixture was incubated at 37 C for 2 h

The first-round optimization led to Compound 70 , which contains a 5-methyl-1-phenyl benzimidazole moiety and exhibited an excellent increase in potency (IC 50 : 52 nM)