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Specifically, the inclusion of the SURPASS-CVOT trial, which compares tirzepatide against dulaglutide rather than semaglutide, is explicitly justified as it provides vital contextual cardiovascular outcome data for tirzepatide in the absence of a completed head-to-head cardiovascular trial between the two primary agents
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The purified solution is then concentrated and lyophilized or spray-dried to produce a loose powder
Blood pressure monitoring is required, as both components can increase blood pressure and heart rate
This is why insulin, for example, must be injected
In addition to prescribing GLP-1 medications, a physician can recommend comprehensive screening to assess for contraindications and provide dose guidance
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