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Well done the first author Chang Liu
Multi-agonists Targeting multiple pathways at once While GLP-1 receptors slow gastric emptying and increase satiety, other gut hormones like GIP (glucose-dependent insulinotropic polypeptide) and glucagon also influence energy balance
Specifically, edges between intersection nodes, pathways shared by both DM2 and AD, were assigned the highest weight (3), as these represent core molecular mechanisms directly contributing to both diseases
Pharmacol Res 1991;23:241-6
They can advise based on their specific formulation stability data
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