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Half-life, in plain language: If you inject 5 mg on day 0, about 2.5 mg remains ~6 days later, and ~ 1.25 mg after ~12 days
Marotta R, Risoleo MC, Messina G, Parisi L, Carotenuto M, Vetri L, Roccella M (2020) The neurochemistry of autism
To note, Pinchera et al
Plasma concentrations decline with age from approximately 200 ng/mL in early adulthood to around 80 ng/mL by age 60
Cipolat, S., de Brito, O
(38830068) Recently, there has been a trend towards using higher maintenance doses, with 1.5 grams q12 being used initially for most patients in status epilepticus
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