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The protocols that showed results used defined cycles (typically 10 to 20 days) followed by extended breaks (4 to 6 months)
S.SelkoeD
3,4 For instance, following diet-induced weight loss, there is an observed increase in ghrelin and GIP and decrease in leptin, peptide YY (PYY), cholecystokinin (CCK), amylin, insulin, and GLP-1 from baseline
PMCID: PMC9542252
Getting outside, moving your body, and finding community are just as important as the supplements you put in your shaker bottle
You need a high dose to create the caloric deficit required for rapid weight loss, but maintaining a lower body weight requires a smaller ongoing intervention
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