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When medication is discontinued, many people struggle with: returning hunger rebound eating weight regain continued gut discomfort unresolved metabolic dysfunction The underlying drivers were never corrected
Some patients have also experienced a hypersensitivity reaction following intramuscular injection that has resulted in anaphylactic shock and death
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A 2006 British Journal of Dermatology study found afamelanotide increased eumelanin production by 3.5-fold in Type I skin versus 1.8-fold in Type III skin, because the peptides effect scales with existing melanocyte capacity
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