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Semaglutide has been associated with early worsening of diabetic retinopathy in clinical trials, particularly in patients with pre-existing retinopathy and rapid improvement in glycaemic control
All participants in the oral-semaglutide group initiated oral semaglutide at 3 mg once daily
In zebrafish, NPY promotes sleep via inhibition of noradrenergic signaling and loss-of-function mutations of NPY resulted in decreased sleep (Singh et al
Circadian Regulation Influences pineal gland function and melatonin secretion, supporting healthy circadian rhythms, sleep quality, and hormonal balanceall critical for optimal aging and metabolic health
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