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PLoS ONE 9 , e113234 (2014)
It catalyzes the addition of glycine to -glutamylcysteine created by GCL to form GSH, -L-glutamyl-L-cysteinyl-glycine, a reaction again driven by the hydrolysis of ATP
SOD is necessary because superoxide reacts with sensitive and critical cellular targets
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Our bodies make glutathione in the liver our main detoxification organ
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress
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