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10.1371/journal.pone.0025269 PLoS One 94 ShelburneJ

How GLP-1 Receptor Agonists Work Native GLP-1 has a short half-life of just 1-2 minutes because it is rapidly broken down in the blood by the enzyme dipeptidyl peptidase 4 (DPP-4)

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Additionally, medications used to treat lupus, like corticosteroids, can contribute to weight gain

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