polymethoxyflavones promote thermogenesis of brown and white adipose tissue in high-fat diet induced C57BL/6J mice Guangning Kou, Yan Hu, Zixiao Jiang, Zhenqing Li, Peiyuan Li, Hongjie Song, Qiyang Chen, Zhiqin Zhou, Quanjun Lyu Journal of Functional Foods.2020
That is the largest weight loss result ever recorded in a late-stage pharmaceutical trial for an obesity drug
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The GLP-1 receptor activation reduces appetite by signaling fullness to the brain
Some act quickly, while others take longer to produce an effect
The role of central GIP receptors remains less well characterized and is an area of ongoing investigation