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The gut microbiota significantly influences GABA synthesis and metabolism ( Clostridium butyricum , can modulate the expression of GABA-related genes in intestinal epithelial cells and immune cells through SCFAs, including butyric acid, thereby affecting GABA synthesis and release (Liu Z

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BPC-157 and TB-500 have shown favorable safety profiles in preclinical research, with few adverse effects reported

Nutrients 12 (5), 1344