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Acute liver injury has been reported with GLP-1 receptor agonists, though establishing direct causation is difficult because many users have pre-existing liver conditions that could independently cause enzyme elevations

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What we know: The same total amount reaches your bloodstream - Clinical trial data confirmed equivalent overall absorption (AUC and Cmax) across all three sites Yet reported side effect rates differed substantially - Thigh showed roughly half the nausea rate of abdomen despite identical systemic exposure Possible explanations include differences in absorption rate (even if total absorption is equal), local tissue effects at the injection site, or simply statistical variation in a relatively small study

For more details, visit the IWBF Anti-Doping webpage or WADAs official website

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